Inflammation is the immune system’s first reaction against injury
and invaders. Inflammation is marked by pain, swelling, redness and
heat. Short term it is effective at destroying pathogens and repairing
damage. Long term it causes severe joint and tissue damage and leads
to many serious conditions such as heart disease, Alzheimer’s and
macular degeneration
Anti-inflammatory Drug Dangers, over 6 billion spent annually2004
Vioxx voluntarily recalled due to increased heart attack and stroke.
University of Pennsylvania Medical Center found that Celebrex increases
the risk of heart attack and/or stroke by 34%. New Jersey University
of Medicine and Dentistry found rats given Vioxx or Celebrex took
double the time to heal and developed weakened bone.. Hundreds of
deaths worldwide and thousands of cases of severe gastrointestinal
bleeding have occurred in those taking Celebrex over the last three
years.. The Lancet found that NSAIDS contribute to cartilage destruction
in the hips of 294 patients taking NSAIDS. . NSAIDS cause 20,000 deaths
in the U.S. annually. Over 120,000 North Americans are hospitalized
with the side effects of NSAIDS. . Acetaminophen overdose is the leading
cause of acute liver failure and causes ten percent of all cases of
kidney failure..
Celadrin is a patented combination of special cetylated, esterifed
fatty acids containing: Cetyl myristoleate, Cetyl myristate, Cetyl
palmitoleate, Cetyl laureate, Cetyl palmitate, Cetyl oleate. Celadrin
is stable in the presence of oxygen unlike other EFAs. Celadrin reduces
inflammation and pain quickly with no side effects. Available in cream
and capsule form.. Celadrin has been published twice in the internationally
acclaimed Journal of Rheumatology. Celadrin systematically enhances
and lubricates cell membranes. Celadrin applied topically works in
just 30 minutes with significant improvement.
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Celadrin Cream (no menthol) Osteoarthritis. University of Connecticut.
40 patients with osteoarthritis of the knee. Topical application of
7.5 % Celadrin cream (no menthol) twice daily morning and night..
Randomly assigned, placebo controlled, double-blind trial. Tests were
performed at baseline, once at 30 minutes and 30 days after treatment.
Range of motion, getting up and down from a chair, step down and extended
reach were measured. Compliance was 100% for both treatment and placebo
groups. No side effects were noted. No arthritis drugs only lifesaving
drugs. Improvement on all parameters tested but especially in stair
climbing and the ability to rise from a chair was substantial at 30
minutes. Only treatment group had significant difference at T2 and
T3Journal of Rheumatology 2004, April 3(4):767-774.
Celadrin Cream with menthol Osteoarthritis . 7.5 % Celadrin cream
with Menthol (1 week trial). Dr. Kraemer as an extension of the J
of Rheumatology study. To verify the addition of menthol to the Celadrin
cream. This study used a single treatment group with a pre-post experimental
design to examine the percentage changes. Individuals diagnosed with
OA of the knee and severe pain of the elbow and wrist were tested
for pain and functional performance before and after 1 week of treatment
with a topical cream consisting of Celadrin and menthol applied twice
per day morning and evening.. In individuals with knee OA, a significant
approximately 12 percent improvement was noted in stair-climbing ability
"up-and-go" performance saw a 12 percent improvement in
times, balance and strength improved by 16.5 percent, and range of
motion improved by about 3.5 percent. Reductions in pain were also
noted.. In individuals with severe pain of the elbow and wrist, significant
improvements in dynamic (about 22 and 24.5 %, respectively) and isometric
(about 33 and 42%, respectively). The percentage changes were consistent
with the work published in the J of Rheumatology using Celadrin without
menthol. Journal of Strength and Conditioning
Celadrin Cream (no menthol) Osteoarthritis. 7.5% Celadrin cream containing
no menthol. Dr. Kraemer examined the effects of Celadrin cream on
static postural stability and plantar pressures in patients with osteoarthritis
(OA) in the knee(s). 40 patients with knee OA were randomly assigned
to 1 of 2 topical treatment groups to either receive Celadrin cream
or placebo.. Patients were evaluated at baseline and following a 30-day
treatment. In the Celadrin group, a significant reduction in the measure
center of pressure (COP) excursion length and velocity were observed
at 30 days, whereas no significant differences were observed in the
placebo group. No significant differences in mean forefoot, rear foot,
or rear foot-to-forefoot plantar pressure ratios were observed in
either group at 30 days.. . These data indicate that 30 days of treatment
with Celadrin topical cream improves static postural stability in
patients with knee OA presumably due to pain relief during quiet standing..
Such over-the-counter treatment may help improve the exercise trainability
of people with OA. Journal of Strength and Conditioning May 2005
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Celadrin Capsules & Osteoarthritis
64 patients with osteoarthritis of the knee. Evaluated for knee range
of motion and function at baseline, day 30 and day 68. Randomized,
double-blind, placebo controlled trial. After 68 days, patients treated
with soft gel Celadrin exhibited significant increase in knee flexing
compared to placebo. Patient responses to pain, discomfort, walking
distances and physical function indicated a significant shift towards
functional improvement in the Celadrin group with OA of the knee compared
to a modest improvement in the placebo group.. 58% of Celadrin group
had a significant reduction in pain Journal of Rheumatology 2002 Aug;
29(8):1708-1712
Celadrin Cream & Psoriasis
Double-blind, placebo controlled trial. Dermatologist assigned an
initial severity score for each patient using a 6 point scale (0=no
psoriasis; 5=significant psoriasis). Evaluation included skin scales,
patchiness, raised skin, redness, dryness and cracks.. 10% Celadrin
super strength (non-menthol) cream was applied twice per day morning
and night. Each participant was evaluated at 7 and 14 days. Measurable
improvement was noted in all symptoms. Some patients had reached a
plateau in their current treatments and after 14 days of topical Celadrin
application had marked improvementThird party pilot trial performed
by Life Management Group
Celadrin Cream & Wrinkles
28 subjects between the ages of 25 and 65 average age 45. Washout
period of 10 days where no moisturizing cream was used. No change
in diet only a request to drink water and limit sun exposure.. 10%
Celadrin super strength cream was applied twice per day morning and
night for 21 days. Likert-type scale was used where the changes in
skin wrinkling were noted. Each participant was evaluated after 21days
of application.. Measurable improvement was noted in all areas by
both the subject and dermatologist. An increase in skin permeability,
improvement in roughness and thickening of the skin and it was found
to be firmer and better hydrated. Third party pilot trial performed
by Life Management Group, participants were staff and faculty of the
University of California.
Celadrin
Capsules & Osteoarthritis in Dogs. 20% or 53 million dogs in the
U.S have osteoarthritis. Standard treatments are similar to humans
including NSAIDS, aspirin or acetaminophen. Side effects in animals
include ulcer, diarrhea and vomiting among others. . 24 dogs completed
the study. Dogs were evaluated prior to and 30 days after supplementation
with Celadrin in a dose of 150mg per 20 lbs.. 75% of owners said pets
were happier, had an improved temperament, and were more energetic.
Vet reported improved gait and stair climbing after 30 days of supplementation
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Celadrin & Glucosamine. Celadrin is effective at halting the joint-damaging
inflammatory process.. Glucosamine can repair damage already done
to affected joints.. Celadrin works by providing continuous lubrication
and allowing the cell membrane to repel inflammatory messengers Celadrin
stops the cascade of inflammation and the assaults on the membrane,
which cause stiffness.. The dual action of Celadrin and glucosamine
provides rapid joint cushioning, quickly alleviating inflammation,
building cartilage and restoring the entire joint area.. Excellent
results have been reported by those individuals with OA and RA who
have adopted the combination treatment of Celadrin and glucosamine.
Mechanism
of Action. Celadrin inhibits inflammation in endothelial cells (thin
cells that line the inside of some body cavities).. Celadrin reduces
the production of the immune factor IL-6 and controls other immune
factors responsible for inflammation.. Celadrin plays a role in the
lubrication of affected joints.. Celadrin’s special fatty acids
have been shown to reduce skin inflammation, while providing an emollient
effect at the site of psoriasis.. Celadrin also works by inhibiting
arachidonic acid, one of the main promoters of the inflammatory cascade
of immune factors, by inhibiting 5-lipoxygenase — another mediator
of inflammation.. It may also alter cellular membranes, protecting
them from the action of inflammatory immune messengers.
C-Reactive Protein. C-reactive protein is produced by the liver during
an inflammatory response.. Those with hs-CRP levels above 3.0 mg/L
have a risk of heart attack or stroke three times higher than the
risk of those with a reading of less than 0.5 mg/L.. High hs-CRP is
found in those with the most severe forms of macular degeneration.
Those persons with high hs-CRP have triple the risk of developing
colon cancer. Those persons with high hs-CRP have 4 times the risk
of developing Type-2 diabetes Optimal: Less than 0.5 mg/L to 1.0 mg/L
Should be monitored: Between 1.0 mg/L and 3.0 mg/L Indicates high
levels of inflammation: Over 3.0 mg/L. Those taking Celadrin have
shown lowered hs-CRP levels anecdotally.
Toxicology and toxicity studies show Celadrin to be exceptionally
safe. Celadrin is comprised of special fatty acids known to be very
safe. There have been no reported side effects in any study to date..
Participants in the study continued their heart medications without
any interactions.. Safety of Celadrin
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